efavirenz will increase the level or influence of celecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.aspirin/citric acid/sodium bicarbonate will increase the level or effect of celecoxib by acidic (anionic) drug Levels of competition for renal tubular clearance. Small/Importance Unidentified.78 situations the MHDD (dete